Lifestyle analyses

A genetic test examines DNA, the genetic information contained within a person's cells. Each person's DNA is a unique blueprint that provides instructions for a person's physical traits, such as eye color, hair texture, height, and various health conditions.

 

DNA is a molecule shaped like a spiral staircase. The long DNA molecules in our cells are organized into pieces called chromosomes. Humans have 23 pairs of chromosomes, and chromosomes are further organized into short segments of DNA called genes.

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Cells use the information written in our genes to make proteins. Some proteins give cells their shape and structure. Others help cells carry out biological processes such as digesting food or carrying oxygen in the blood, and still others make up the body's immune system. In genetic testing, researchers scan a patient's DNA sample to detect any sequences that are changed or different from the general population. A DNA sample for genetic testing can be obtained from any tissue, including blood and a variety of biological fluids, such as amniotic fluid and saliva. Reliable genetic analysis begins with the correct collection of DNA samples. Swiss law covers the analysis of “genetic tests outside the medical field” (see also the Swissmedic website: https://www.bag.admin.ch/bag/it/home/medizin-und-forschung/genetische-untersuchungen/info-fachpersonen/veranlassung-gentests.html) that, for example, provide knowledge about athletic ability and optimal nutrition. Health professionals such as dietitians, physiotherapists, chiropractors and osteopaths may prescribe genetic tests outside of the medical field that concern physiological characteristics such as metabolic genetic tests to optimize nutrition, genetic tests that provide information on the conformation of the muscles, and the physical resistance of the organism.

 

The LDM DNA kit from saliva/mouth smear offers a non-invasive, reliable and easy-to-use method of sample collection, allowing the collection of high amounts of DNA of high quality and decreasing the complexity of transport, handling and storage of samples due to the long-term stability of DNA at room temperature. The sample can be shipped using the standard postal system.

 

LDM Lifestyle DNA tests are performed in Switzerland by the Molecular Diagnostic Laboratory of Lugano a facility authorized by the Federal Department of Health, which employs trained personnel, using an analytically validated process. Although genetic tests can provide important information on particular health conditions and their prevention, there are still limitations. For example, in a healthy person, a positive genetic test result does not mean that he or she will develop a different health condition than the current one. On the other hand, in some situations, a negative result does not guarantee that a certain disorder will not occur. Test results are intended for educational purposes only and not for diagnostic use. Any results from the analysis of genome sequence information that may be considered relevant should be confirmed using alternative tests with specialist advice.

Genetic test
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Gut Microbiota

Gut microbiota refers to the entire population of microorganisms (bacteria, viruses, parasites and non-pathogenic fungi) that live in our gastro-intestinal tract.

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Lactose intolerance

At the basis of the symptoms of lactose intolerance there is a defect in the lactase enzyme in the intestinal microvilli which leads to the lack of hydrolysis of lactose into glucose and galactose and a consequent malabsorption syndrome.

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Ruling out celiac disease

The predisposition to gluten intolerance is transmitted through the alleles of the major histocompatibility complex class II. The sum of the frequencies of the HLA genes DQA1*0501, DQB1*0201 (DQ2) and DQA1*0310 and DQB1*0302 (DQ8) are found in 90% of celiac patients. The DQ2 complex is also present in 25% of the general population.

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Laboratorio di Diagnostica Molecolare SA
LDM IT
Via G. Petrini 2
CH-6900 Lugano
+41 (0)91 9603700
info@ldm.ch

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